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2005 - 2009

Institut für Organische Chemie und Biochemie, Albert-Ludwigs-Universität, Freiburg


Buedenbender, S., Rachid, S., Müller, R. & Schulz, G.E. (2009). Structure and action of the myxobacterial chondrochloren halogenase CndH: A new variant of FAD-dependent halogenases. J. Mol. Biol. 385, 52-530.

Buedenbender , S. & Schulz, G.E. (2009). Structural base for enzymatic cyclodextrin hydrolysis. J. Mol. Biol. 385, 606-617.

Schulz, G. E. (2009). The dominance of symmetry in the evolution of homo-oligomeric proteins. J. Mol. Biol., in press.


Grueninger, D. & Schulz, G. E. (2008). Domain motions supporting the reaction catalyzed by L rhamnulose 1 phosphate aldolase. Biochemistry, 47, 607-614.

Grueninger, D., Treiber, N., Ziegler, M.O.P., Koetter, J., Schulze, M.-S. & Schulz, G.E. (2008). Designed protein-protein association. Science, 319, 206-209.

Ziegler, M.O.P., Jank, T., Aktories, K. & Schulz, G.E. (2008). Conformational changes and reaction of clostridial glycosylating toxins. J. Mol. Biol. 377, 1346-1356.

Ziegler, K., Benz, R. & Schulz, G.E. (2008). An α-helical porin from Corynebacterium glutamicum. J. Mol. Biol. 379, 482-491.

Jank, T., Ziegler, M.O.P., Schulz, G.E. & Aktories, K. (2008). Inhibition of the glucosyltransferase activity of clostridial Rho/Ras-glucosylating toxins by castanospermine. FEBS Lett. 582, 2277-2282.

Treiber, N. & Schulz, G.E. (2008). Structure of 2,6-dihydroxypyridine-3-hydroxylase from a nicotine-degrading pathway. J. Mol. Biol. 379, 94-104.

Treiber, N., Reinert, D.J., Carpusca, I., Aktories, K. & Schulz, G.E. (2008). Structure and mode of action of a mosquitocidal holotoxin with its four ricin B type lectin domains. J. Mol. Biol. 381, 150-159.


Schulz, G.E. (2007). Protein crystallization. In: Comprehensive Medicinal Chemistry II (Taylor, J. B. & Triggle, D. J., Eds.), vol. 3, pp. 433-447, Elsevier, Oxford.

Schleberger, C., Sachelaru, P., Brandsch, R. & Schulz, G.E. (2007). Structure and action of a C-C bond cleaving α/β-hydrolase involved in nicotine degradation. J. Mol. Biol. 367, 409-418.

Zocher, G., Winkler, R., Hertweck, C. & Schulz, G.E. (2007). Structure of the N-oxygenase AurF from Streptomyces thioluteus. J. Mol. Biol. 373, 65-74.

Mittler, M., Bechthold, A. & Schulz, G.E. (2007). Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin. J. Mol. Biol. 372, 67-76.

Grueninger, D. & Schulz, G.E. (2007). Substrate spectrum of L-rhamnulose kinase related to models derived from two ternary complex structures. FEBS Lett. 581, 3127-3130.

Zocher, G., Wiesand, U. & Schulz, G.E. (2007). High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli. FEBS J. 274, 5382-5389.

Winkler, R., Zocher, G., Richter, I., Friedrich, T., Schulz, G.E. & Hertweck, C. (2007). A binuclear manganese cluster catalyzing radical-mediated N-oxygenation. Angew. Chem. Int. Ed. 46, 8605-8608.



Bannwarth, M., Heckmann-Pohl, D., Bastian, S., Giffhorn, F. & Schulz, G.E. (2006). Reaction geometry and thermostable variant of pyranose 2-oxidase from the white-rot fungus Peniophora sp. Biochemistry 45, 6587-6595.

Kloer, D.P., Welsch, R., Beyer, P. & Schulz, G.E. (2006). Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. Biochemistry 45, 15197-15204.

Kloer, D.P. & Schulz, G.E. (2006). Structural and biological aspects of carotenoid cleavage. Cell. Molec. Life Sci. 63, 2291-2303.

Kraft, M., Schleberger, C., Weckesser, J. & Schulz, G.E. (2006). Binding structure of the leucine aminopeptidase inhibitor microginin FR1. FEBS Lett. 580, 6943-6947.

Reinert, D.J., Carpusca, I., Aktories, K. & Schulz, G.E. (2006). Structure of the mosquitocidal toxin from Bacillus sphaericus. J. Mol. Biol. 357, 1226-1236.

Grueninger, D. & Schulz, G.E. (2006). Structure and reaction mechanism of L-rhamnulose kinase from Escherichia coli. J. Mol. Biol. 359, 787-797.

Schleberger, C., Hochmann, H., Aktories, K. & Schulz, G.E. (2006). Structure and action of the binary C2 toxin from Clostridium botulinum. J. Mol. Biol. 364, 705-715.

Schulz, G.E. (2006). Channels in the outer membrane of Mycobacter. In: Structural Biology of Membrane Proteins (Grisshammer, R. & Buchanan, S. K., Eds.), pp. 235-251, Royal Society of Chemistry, Cambridge/UK.

Kloer, D.P., Hagel, C., Heider, J., & Schulz, G.E. (2006). Crystal structure of ethylbenzene dehydrogenase from Aromatoleum aromaticum. Structure 14, 1377-1388.



Ikeda, K., Schiltz, E., Fujii, T., Takahashi, M., Mitsui, K., Kodera, Y., Matsushima, A., Inada, Y., Schulz, G.E. & Nishimura, H. (2005). Phenylalanine ammonia-lyase modified with polyethylene glycol: Potential therapeutic agent for phenylketonuria. Amino Acids 29, 283-287.

Claus, M.T., Zocher, G.E., Maier, T.H.P. & Schulz. G.E. (2005). The structure of the O-acetylserine sulfhydrylase isoenzyme CysM from Escherichia coli. Biochemistry 44, 8620-8626.

Mosbacher, T.G., Mueller, M. & Schulz, G.E. (2005). Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens. FEBS J. 272, 6067-6076.

Birringer, M.S., Claus, M.T., Folkers, G., Kloer, D.P., Schulz, G.E. & Scapozza, L. (2005). Structure of a type II thymidine kinase with bound dTTP. FEBS Lett. 579, 1376-1382.

Jank, T., Reinert, D.J., Giesemann, T., Schulz, G E. & Aktories, K. (2005). Change of the donor substrate specificity of Clostridium difficile toxin B by site-directed mutagenesis. J. Biol. Chem. 280, 37833-37838.

Becker, L., Bannwarth, M., Meisinger, C., Hill, K., Model, K., Krimmer, T., Casadio, R., Truscott, K. N., Schulz, G.E., Pfanner, N. & Wagner, R. (2005). Preprotein translocase of the outer mitochondrial membrane: reconstituted Tom40 forms a characteristic TOM pore. J. Mol. Biol. 353, 1011-1020.

Koetter, J.W.A. & Schulz, G.E. (2005). Crystal structure of 6-hydroxy-D-nicotine oxidase from Arthrobacter nicotinovorans. J. Mol. Biol. 352, 418-428.

Reinert, D.J., Jank, T., Aktories, K. & Schulz, G.E. (2005). Structural basis for the catalytic function of Clostridium difficile toxin B. J. Mol. Biol. 351, 973-981.

Mosbacher, T.G., Bechthold, A. & Schulz, G.E. (2005). Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes. J. Mol. Biol. 345, 535-545.

Ceruti, M., Balliano, G., Rocco, F., Lenhart, A., Schulz, G.E., Castelli, F. & Milla, P. (2005). Synthesis and biological activity of new iodoacetamide derivatives on mutants of squalene-hopene cyclase. Lipids 40, 729-735.

Kloer, D.P., Ruch, S., Al-Babili, S., Beyer, P. & Schulz, G.E. (2005). The structure of a retinal-forming carotenoid oxygenase. Science 308, 267-269.

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